نوع مقاله : مقاله پژوهشی
نویسندگان
1 دانشجوی کارشناسی ارشد، علوم و صنایع غذایی، دانشگاه تبریز
2 استاد، علوم و صنایع غذایی، دانشگاه تبریز
3 دانشیار، دانشگاه علوم پزشکی تبریز
4 دانشجوی دکترا، دانشگاه علوم پزشکی تبریز
5 دانشیار، علوم و صنایع غذایی، دانشگاه تبریز
چکیده
کلیدواژه‌ها
عنوان مقاله [English]
نویسندگان [English]
Encapsulation of phenolic compounds as natural antioxidants is one of the ways in order to inhibit oxidation and to improve their absorption. Liposomes are colloidal vesicles comprised of polar lipids which can be used to entrap hydrophilic, hydrophobic and amphipathic compounds. The main objective of this study is to evaluate the capability of liposomes to encapsulate Urtica dioica L. extract and determine colloidal and antioxidant properties of Urtica dioica extract loaded nanoliposomes. In this study nanoliposomes containing Urtica dioica L. extract were prepared from various quantities of phosphatidylcholine (PC) and cholesterol included (60-0, 50-10, 40-20, 30-30 miligeram) Equivalent (8-0, 7-3, 5-5, 4-8 mili molar) by thin-film hydration and sonication method. Experiments including particle size, encapsulation efficiency, antioxidant activity, encapsulation stability and turbidity were determined. The particle size and size distribution (span) data were in the range of 81-94 nm, and 0.81- 0.88, respectively. The effect of various concentrations of lecithin-cholesterol on the size of nanoliposomes was insignificant (P
کلیدواژه‌ها [English]
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