A systematic review and meta-analysis of extraction and identification of barberry bioactive compounds

نوع مقاله : مقاله مروری

نویسندگان

1 Department of Food Science and Technology, Qa.C., Islamic Azad University, Qazvin, Iran.

2 Department of Food Science and Technology, Qa .C., Islamic Azad University, Qazvin, Iran.

3 Department of Food Science and Technology,., Islamic Azad University, Qazvin, Iran.

چکیده

Barberry (Berberis spp.), a genus in the Berberidaceae family with 650 species, holds significant potential in the pharmaceutical and food industries. This review assesses the available information and carries out a meta-analysis of published research on bioactive compounds extracted from various Berberis species. PubMed, Web of Science, and Scopus databases were searched extensively for articles published between 2009 and 2023. This analysis included 38 relevant articles, including those that evaluated multiple extraction methods. Four extraction methods involving different techniques and equipment were identified in the included studies and comparatively evaluated in this systematic review and meta-analysis. According to our meta-analysis of the published data, the frequency of use of the methods was as follows: Press Extraction (PE) (22.72%), Maceration Extraction (ME) (20.45%), Ultrasound-Assisted Extraction (UAE) (18.18%), and Subcritical Water Extraction (SWE) (6.82%). The most common solvents used in the selected studies were water (42.86%) and methanol (22.86%). In addition, this review investigated, based on the reported data, the effects of the extraction method on antioxidant activity (DPPH), Total Phenolic Content (TPC), and Total Anthocyanin Content (TAC). The results showed that, among the reported techniques, SWE was generally associated with the highest DPPH values. Moreover, UAE was most frequently used for determining TPC and TAC on a dry-weight basis, whereas ME and SWE were more commonly applied when data were expressed on a solution basis.

چکیده تصویری

A systematic review and meta-analysis of extraction and identification of barberry bioactive compounds

تازه های تحقیق

  • This study presents the first comprehensive systematic review and meta-analysis of extraction methods and bioactive compound identification in Berberis
  • Comparative evaluation of four major extraction techniques provides quantitative insights into their relative efficiency in recovering bioactive compounds.
  • The research identifies solvent usage trends across studies, revealing water and methanol as the dominant extraction solvents for Berberis
  • The study correlates extraction method performance with antioxidant activity (DPPH), total phenolic content (TPC), and total anthocyanin content (TAC), offering a unified understanding of method efficacy.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

A systematic review and meta-analysis of extraction and identification of barberry bioactive compounds

نویسندگان [English]

  • Akram Sharifi 1
  • Atefe Taherkhani 2
  • Nazanin Amirahmadi 3
1 Department of Food Science and Technology, Qa.C., Islamic Azad University, Qazvin, Iran.
2 Department of Food Science and Technology, Qa .C., Islamic Azad University, Qazvin, Iran.
3 Department of Food Science and Technology, ., Islamic Azad University, Qazvin, Iran.
چکیده [English]

Barberry (Berberis spp.), a genus in the Berberidaceae family with 650 species, holds significant potential in the pharmaceutical and food industries. This review assesses the available information and carries out a meta-analysis of published research on bioactive compounds extracted from various Berberis species. PubMed, Web of Science, and Scopus databases were searched extensively for articles published between 2009 and 2023. This analysis included 38 relevant articles, including those that evaluated multiple extraction methods. Four extraction methods involving different techniques and equipment were identified in the included studies and comparatively evaluated in this systematic review and meta-analysis. According to our meta-analysis of the published data, the frequency of use of the methods was as follows: Press Extraction (PE) (22.72%), Maceration Extraction (ME) (20.45%), Ultrasound-Assisted Extraction (UAE) (18.18%), and Subcritical Water Extraction (SWE) (6.82%). The most common solvents used in the selected studies were water (42.86%) and methanol (22.86%). In addition, this review investigated, based on the reported data, the effects of the extraction method on antioxidant activity (DPPH), Total Phenolic Content (TPC), and Total Anthocyanin Content (TAC). The results showed that, among the reported techniques, SWE was generally associated with the highest DPPH values. Moreover, UAE was most frequently used for determining TPC and TAC on a dry-weight basis, whereas ME and SWE were more commonly applied when data were expressed on a solution basis.

کلیدواژه‌ها [English]

  • bioactive compounds
  • meta-analysis
  • extraction
  • phenolic compounds
  • barberry
[1] Shekarabi, S. P. H., Mehrgan, M. S., Ramezani, F., Dawood, M. A. O., Van Doan, H., & Moonmanee, T. (2022). Effect of dietary barberry fruit (Berberis vulgaris) extract on immune function, antioxidant capacity, antibacterial activity, and stress-related gene expression of Siberian sturgeon (Acipenser baerii). Aquac. Rep., 23, 101041. https://doi.org/10.1016/j.aqrep.2022.101041
[2] Abdykerimova, S., Sakipova, Z., Nakonieczna, S., Koch, W., Biernasiuk, A., & Grabarska, A. (2020). Superior antioxidant capacity of Berberis iliensis—HPLC-Q-TOF-MS-based phytochemical studies and spectrophotometric determinations. Antioxidants, 9(6), 504. https://doi.org/10.3390/antiox9060504
[3] Radziejewska-Kubzdela, E., Szwengiel, A., Ratajkiewicz, H., & Nowak, K. (2020). Effect of ultrasound, heating and enzymatic pre-treatment on bioactive compounds in juice from Berberis amurensis Rupr. Ultrason. Sonochem., 63, 104971. https://doi.org/10.1016/j.ultsonch.2020.104971
[4] Gholizadeh-Moghadam, N., Hosseini, B., & Alirezalu, A. (2019). Classification of barberry genotypes by multivariate analysis of biochemical constituents and HPLC profiles. Phytochem. Anal., 30(4), 385–394.
[5] Sensu, E., Kasapoglu, K. N., Gultekin-Ozguven, M., Demircan, E., Arslaner, A., & Ozcelik, B. (2021). Orange, red and purple barberries: Effect of in vitro digestion on antioxidants and ACE inhibitors. LWT–Food Sci. Technol., 140, 110820.
[6] Sarraf, M., Beig Babaei, A., & Naji-Tabasi, S. (2019). Investigating functional properties of barberry species: An overview. J. Sci. Food Agric., 99(12), 5255–5269. https://doi.org/10.1002/jsfa.9804
[7] Sasidharan, S., Chen, Y., Saravanan, D., Sundram, K., & Latha, L. Y. (2011). Extraction, isolation and characterization of bioactive compounds from plants’ extracts. Afr. J. Tradit. Complement. Altern. Med., 8(1).
[8] Chemat, F., Vian, M. A., & Cravotto, G. (2012). Green extraction of natural products: Concept and principles. Int. J. Mol. Sci., 13(7), 8615–8627.
[9] Sharifi, A., & Khoshnoudi-Nia, S. (2022). Ranking novel extraction systems of seedless barberry (Berberis vulgaris) bioactive compounds with fuzzy logic-based term weighting scheme. Sustain. Chem. Pharm., 25, 100561.
[10] Samira, O., Laila, B., Moussa, N. A., Mohamed, I., Devkota, K., & Abdelhakim, B. (2024). Recent advances in the extraction of bioactive compounds from plant matrices and their use as potential antioxidants for vegetable oils enrichment. J. Food Compos. Anal., 105995. https://doi.org/10.1016/j.jfca.2024.105995
[11] Azmir, J., Zaidul, I. S. M., Rahman, M. M., Sharif, K., Mohamed, A., & Sahena, F. (2013). Techniques for extraction of bioactive compounds from plant materials: A review. J. Food Eng., 117(4), 426–436.
[12] Demirci, M., Tomas, M., Tekin-Çakmak, Z. H., & Karasu, S. (2021). Berberis crataegina DC. as a novel natural food colorant source: Ultrasound-assisted extraction optimization using response surface methodology and thermal stability studies. Food Sci. Technol., 42, e13421. https://doi.org/10.1590/fst.13421
[13] Niakousari, M., & Tahsiri, Z. (2017). Subcritical water technology for extraction of phytochemical compounds. J. Med. Plants, 16(62), 94–107. http://dorl.net/dor/20.1001.1.2717204.2017.16.62.1.4
[14] Nakajima, H. (2013). Mass transfer: Advances in sustainable energy and environment oriented numerical modeling. BoD–Books on Demand.
[15] Verep, D., Ateş, S., & Karaoğul, E. (2023). A review of extraction methods for obtaining bioactive compounds in plant-based raw materials. Bartın Orman Fak. Derg., 25(3), 492–513. https://doi.org/10.24011/barofd.1303285
[16] Al Juhaimi, F., Ozcan, M. M., Uslu, N., Ghafoor, K., Babiker, E. E., & Adiamo, O. Q. (2018). The effects of conventional heating on phenolic compounds and antioxidant activities of olive leaves. J. Food Sci. Technol., 55(10), 4204–4211.
[17] Khoshnoudi-Nia, S., Forghani, Z., & Jafari, S. M. (2022). A systematic review and meta-analysis of fish oil encapsulation within different micro/nanocarriers. Crit. Rev. Food Sci. Nutr., 62(8), 2061–2082.
[18] Sharif, N., Khoshnoudi-Nia, S., & Jafari, S. M. (2020). Nano/microencapsulation of anthocyanins: A systematic review and meta-analysis. Food Res. Int., 132, 109077. https://doi.org/10.1016/j.foodres.2020.109077
[19] Oliveira, C. B. D. d., & Sakai, O. A. (2020). Clean technologies for obtaining biocomposites of Brazilian ginseng Pfaffia glomerata (Spreng.) Pedersen: A review. Eur. J. Med. Plants, 31(14), 18–31.
[20] Junior, F. D. B., Marquezi, L. C., Sakai, O. A., & Terhaag, M. M. (2021). Efeitos de diferentes técnicas extrativas na obtenção da β-ecdisona proveniente de Pfaffia glomerata: Um estudo de revisão. Res. Soc. Dev., 10(4), e24610414147.
[21] Rodrigues Machado, A., Atatoprak, T., Santos, J., Alexandre, E. M., Pintado, M. E., & Paiva, J. A. (2023). Potentialities of the extraction technologies and use of bioactive compounds from winery by-products: A review from a circular bioeconomy perspective. Appl. Sci., 13(13), 7754. https://doi.org/10.3390/app13137754
[22] Johnson, R. A., & Bhattacharyya, G. K. (2019). Statistics: Principles and methods. John Wiley & Sons.
[23] Santos, T. R. J., & Santana, L. C. L. A. (2022). Conventional and emerging techniques for extraction of bioactive compounds from fruit waste. Braz. J. Food Technol., 25, e2021130. https://doi.org/10.1590/1981-6723.13021
[24] Stephane, F. F. Y., Jules, B. K. J., Batiha, G., Ali, I., & Bruno, L. N. (2021). Extraction of bioactive compounds from medicinal plants and herbs. Nat. Med. Plants.
[25] Akbulut, M., Calisir, S., Marakoglu, T., & Coklar, H. (2009). Some physicomechanical and nutritional properties of barberry (Berberis vulgaris L.) fruits. J. Food Process Eng., 32(4), 497–511.
[26] Chitgar, M. F., Aalami, M., Kadkhodaee, R., Maghsoudlou, Y., & Milani, E. (2018). Effect of thermosonication and thermal treatments on phytochemical stability of barberry juice copigmented with ferulic acid and licorice extract. Innov. Food Sci. Emerg. Technol., 50, 102–111.
[27] Emam-Djomeh, Z., Seddighi, A., & Askari, G. (2017). Influence of process conditions on the functional properties of spray-dried seedless black barberry (Berberis vulgaris) juice powder. J. Food Process. Preserv., 41(3), e12934.
[28] Naji-Tabasi, S., Emadzadeh, B., Shahidi-Noghabi, M., Abbaspour, M., & Akbari, E. (2021). Physico-chemical properties of powder and compressed tablets based on barberry fruit pulp. J. Food Meas. Charact., 15(3), 2469–2480.
[29] Ozgen, M., Saracoglu, O., & Gecer, E. N. (2012). Antioxidant capacity and chemical properties of selected barberry (Berberis vulgaris L.) fruits. Hortic. Environ. Biotechnol., 53, 447–451.
[30] Alizadeh, H.-R., Mortezapour, H., Akhavan, H.-R., & Balvardi, M. (2021). Physicochemical changes of barberry juice concentrated by liquid desiccant-assisted solar system and conventional methods during the evaporation process. J. Food Sci. Technol., 58, 4370–4381. https://doi.org/10.1007/s13197-020-04919-z
[31] Farhadi Chitgar, M., Aalami, M., Maghsoudlou, Y., & Milani, E. (2017). Comparative study on the effect of heat treatment and sonication on the quality of barberry (Berberis vulgaris) juice. J. Food Process. Preserv., 41(3), e12956.
[32] Mirzaei, M., Emam-Djomeh, Z., & Askari, G. (2021). Spray-drying microencapsulation of anthocyanins of black seedless barberry (Berberis vulgaris). J. Food Process. Preserv., 45(10), e15858.
[33] Aliakbarlu, J., Ghiasi, S., & Bazargani-Gilani, B. (2018). Effect of extraction conditions on antioxidant activity of barberry (Berberis vulgaris L.) fruit extracts. Vet. Res. Forum, 9(4), 361. https://doi.org/10.30466/vrf.2018.33090
[34] Alizadeh-Sani, M., Tavassoli, M., Mohammadian, E., Ehsani, A., Khaniki, G. J., & Priyadarshi, R. (2021). pH-responsive color indicator films based on methylcellulose/chitosan nanofiber and barberry anthocyanins for real-time monitoring of meat freshness. Int. J. Biol. Macromol., 166, 741–750.
[35] Dara, A., Feizy, J., Naji-Tabasi, S., Fooladi, E., & Rafe, A. (2023). Comparison on efficiency of pulse electric field, cold plasma and enzymatic pre-treatments for barberry anthocyanins extraction: Modeling and optimization. Preprint.
[36] Hosseini, S., Gharachorloo, M., Ghiassi-Tarzi, B., & Ghavami, M. (2016). Evaluation of organic acids’ ability for extraction of anthocyanins and phenolic compounds from different sources and their degradation kinetics during cold storage. Pol. J. Food Nutr. Sci., 66(4). https://doi.org/10.1515/pjfns-2015-0057
[37] Belwal, T., Giri, L., Bhatt, I. D., Rawal, R. S., & Pande, V. (2017). An improved method for extraction of nutraceutically important polyphenolics from Berberis jaeschkeana CK Schneid. fruits. Food Chem., 230, 657–666.
[38] Jaberi, R., Kaban, G., & Mukerrem, K. (2022). Effects of some extraction parameters on anthocyanin content of barberry (Berberis vulgaris L.) and its antioxidant activity. Türk. Tarımsal Araştırmalar Derg., 9(1), 41–48.
[39] Mohamadi, M., Maskooki, A., & Mortazavi, S. (2012). Evaluation of antioxidant properties of barberry fruits extracts using maceration and subcritical water extraction (SWE). Int. J. Nutr. Food Eng., 6(9), 699–703.
[40] Belwal, T., Dhyani, P., Bhatt, I. D., Rawal, R. S., & Pande, V. (2016). Optimization of extraction conditions for improving phenolic content and antioxidant activity in Berberis asiatica fruits using response surface methodology (RSM). Food Chem., 207, 115–124. https://doi.org/10.1016/j.foodchem.2016.03.081
[41] Renard, C. M. (2018). Extraction of bioactives from fruit and vegetables: State of the art and perspectives. LWT–Food Sci. Technol., 93, 390–395.
[42]      Taherkhani, A., Sharifi, A., & Koubaa, M. (2024). Optimization of bioactive compound extraction from Iranian brown macroalgae Nizimuddinia zanardini with ultrasound and microwave methods using fuzzy logic. Foods, 13(23), 3837.
[43] Aramrueang, N., Asavasanti, S., & Khanunthong, A. (2019). Leafy vegetables. In Integrated processing technologies for food and agricultural by-products (pp. 245–272). Elsevier.
[44] Cakır, O., & Karabulut, A. (2020). Comparison of two wild-grown Berberis varieties based on biochemical characterization. J. Food Process. Preserv., 44(11), e14844. https://doi.org/10.1111/jfpp.14844
[45] Dimitrijevic, M. V., Mitic, V. D., Rankovic, G. Z., & Miladinovic, D. L. (2020). Survey of antioxidant properties of barberry: A chemical and chemometric approach. Anal. Lett., 53(5), 671–682.
[46] Moldovan, C., Frumuzachi, O., Babota, M., Menghini, L., Cesa, S., & Gavan, A. (2021). Development of an optimized drying process for the recovery of bioactive compounds from the autumn fruits of Berberis vulgaris L. and Crataegus monogyna Jacq. Antioxidants, 10(10), 1579. https://doi.org/10.3390/antiox10101579
[47] Sun, J., Li, Q., Li, J., Liu, J., & Xu, F. (2022). Nutritional composition and antioxidant properties of the fruit of Berberis heteropoda Schrenk. PLoS One, 17(4), e0262622. https://doi.org/10.1371/journal.pone.0262622
[48] Tahsiri, Z., Niakousari, M., Khoshnoudi-Nia, S., & Hosseini, S. M. H. (2017). Sensory evaluation of selected formulated milk barberry drinks using the fuzzy approach. Food Sci. Nutr., 5(3), 739–749.
[49] Homayoonfal, M., Mousavi, S. M., Kiani, H., Askari, G., Khani, M., & Bari, M. R. (2018). The use of an innovative inverse numerical modeling method for the evaluation and parameter estimation of barberry anthocyanins ultrasound-assisted extraction. Chem. Eng. Process., 133, 1–11.
[50] Sharifi, A., Mortazavi, S. A., Maskooki, A., Niakousari, M., & Elhamirad, A. (2013). Optimization of subcritical water extraction of bioactive compounds from barberry fruit (Berberis vulgaris) by using response surface methodology. Int. J. Agric. Crop Sci., 6(2), 89.
[51] Zakaria, S. M., & Kamal, S. M. M. (2016). Subcritical water extraction of bioactive compounds from plants and algae: Applications in pharmaceutical and food ingredients. Food Eng. Rev., 8(1), 23–34.
[52] Rasul, M. G. (2018). Conventional extraction methods used in medicinal plants, their advantages and disadvantages. Int. J. Basic Sci. Appl. Comput., 2, 10–14.
[53] Arias, M., Penichet, I., Ysambertt, F., Bauza, R., Zougagh, M., & Rios, A. (2009). Fast supercritical fluid extraction of low- and high-density polyethylene additives: Comparison with conventional reflux and automatic Soxhlet extraction. J. Supercrit. Fluids, 50(1), 22–28. https://doi.org/10.1016/j.supflu.2009.04.012
[54] Tierney, M. S., Smyth, T. J., Hayes, M., Soler-Vila, A., Croft, A. K., & Brunton, N. (2013). Influence of pressurised liquid extraction and solid–liquid extraction methods on the phenolic content and antioxidant activities of Irish macroalgae. Int. J. Food Sci. Technol., 48(4), 860–869. https://doi.org/10.1111/ijfs.12038
[55] Cui, X., Mayer, P., & Gan, J. (2013). Methods to assess bioavailability of hydrophobic organic contaminants: Principles, operations, and limitations. Environ. Pollut., 172, 223–234. https://doi.org/10.1016/j.envpol.2012.09.013
[56] Cooper, R., & Nicola, G. (2014). Natural products chemistry: Sources, separations and structures. CRC Press.
[57] Azwanida, N. (2015). A review on the extraction methods used in medicinal plants: Principle, strength and limitation. Med. Aromat. Plants, 4(196).
[58] Zhang, Q.-W., Lin, L.-G., & Ye, W.-C. (2018). Techniques for extraction and isolation of natural products: A comprehensive review. Chin. Med., 13(1), 20.
[59] Dean, J. R., & Xiong, G. (2000). Extraction of organic pollutants from environmental matrices: Selection of extraction technique. TrAC Trends Anal. Chem., 19(9), 553–564. https://doi.org/10.1016/S0165-9936(00)00038-8
[60] Chaves, J. O., De Souza, M. C., Da Silva, L. C., Lachos-Perez, D., Torres-Mayanga, P. C., & Machado, A. P. d. F. (2020). Extraction of flavonoids from natural sources using modern techniques. Front. Chem., 8, 507887.
[61] Richter, B. E., Jones, B. A., Ezzell, J. L., Porter, N. L., Avdalovic, N., & Pohl, C. (1996). Accelerated solvent extraction: A technique for sample preparation. Anal. Chem., 68(6), 1033–1039. https://doi.org/10.1021/ac9508199
[62] Hoff, R. B., & Pizzolato, T. M. (2018). Combining extraction and purification steps in sample preparation for environmental matrices: A review of matrix solid phase dispersion (MSPD) and pressurized liquid extraction (PLE) applications. TrAC Trends Anal. Chem., 109, 83–96. https://doi.org/10.1016/j.trac.2018.10.002
[63] Aliakbarlu, J., Mohammadi, S., & Khalili, S. (2014). A study on antioxidant potency and antibacterial activity of water extracts of some spices widely consumed in Iranian diet. J. Food Biochem., 38(2), 159–166.
[64] Mortazavi, S. A., Sharifi, A., Maskooki, A., Niakousari, M., & Elhamirad, A. H. (2014). Optimisation of bioactive compounds extraction from barberry fruit (Berberis vulgaris) using response surface methodology. Res. Innov. Food Sci. Technol., 3(1), 24–11. https://doi.org/10.22101/JRIFST.2014.06.15.312
[65] Boeri, P., Pinuel, L., Dalzotto, D., Monasterio, R., Fontana, A., & Sharry, S. (2020). Argentine Patagonia barberry chemical composition and evaluation of its antioxidant capacity. J. Food Biochem., 44(7), e13254.
[66] Sharifi, A., Niakousari, M., Mortazavi, S. A., & Elhamirad, A. H. (2019). High-pressure CO₂ extraction of bioactive compounds of barberry fruit (Berberis vulgaris): Process optimization and compounds characterization. J. Food Meas. Charact., 13, 1139–1146. https://doi.org/10.1007/s11694-018-00029-9
[67] Kukula-Koch, W., Aligiannis, N., Halabalaki, M., Skaltsounis, A.-L., Glowniak, K., & Kalpoutzakis, E. (2013). Influence of extraction procedures on phenolic content and antioxidant activity of Cretan barberry herb. Food Chem., 138(1), 406–413. https://doi.org/10.1016/j.foodchem.2012.10.045
[68] Och, A., Cwikla, A., Orzechowska, K., & Cwener, A. (2023). Evaluation of the antioxidant activity of Berberis jaeschkeana CK Schneid. fruits using the ABTS assay. Preprint. https://repozytorium.ur.edu.pl/handle/item/9517
[69] Asghari, M., Sahari, M., Kia, S. J., Tavakoli, A., & Barzegar, M. (2022). Berberis integerrima extract: Characterization, antioxidant activity and development of phenolic extract loaded nanofiber. Preprint.
[70] Hadaruga, D. I., Hadaruga, N. G., Bandur, G. N., Rivis, A., Costescu, C., & Ordodi, V. L. (2010). Berberis vulgaris extract/β-cyclodextrin nanoparticles synthesis and characterization. Rev. Chim. (Bucharest), 61, 669–675.
[71] Mahdavi, S. A., Jafari, S. M., Assadpoor, E., & Dehnad, D. (2016). Microencapsulation optimization of natural anthocyanins with maltodextrin, gum Arabic and gelatin. Int. J. Biol. Macromol., 85, 379–385.
[72] Niazmand, R., Yeganehzad, S., & Niazmand, A. (2021). Application of laminated and metalized films to prolong the shelf life of dried barberries. J. Stored Prod. Res., 92, 101809. https://doi.org/10.1016/j.jspr.2021.101809
[73] Och, A., Olech, M., Bak, K., Kanak, S., Cwener, A., & Ciesla, M. (2023). Evaluation of the antioxidant and anti-lipoxygenase activity of Berberis vulgaris L. leaves, fruits and stem and their LC-MS/MS polyphenolic profile. Antioxidants, 12(7), 1467. https://doi.org/10.3390/antiox12071467
[74] Rodoni, L. M., Feuring, V., Zaro, M. J., Sozzi, G. O., Vicente, A. R., & Arena, M. E. (2014). Ethylene responses and quality of antioxidant-rich stored barberry fruit (Berberis microphylla). Sci. Hortic., 179, 233–238.
[75] Lefebvre, T., Destandau, E., & Lesellier, E. (2021). Selective extraction of bioactive compounds from plants using recent extraction techniques: A review. J. Chromatogr. A, 1635, 461770.
 [76] Plotka-Wasylka, J., Rutkowska, M., Owczarek, K., Tobiszewski, M., & Namiesnik, J. (2017). Extraction with environmentally friendly solvents. TrAC Trends Anal. Chem., 91, 12–25. https://doi.org/10.1016/j.trac.2017.03.006
[77] Breslow, R. (2010). The principles of and reasons for using water as a solvent for green chemistry. In Handbook of Green Chemistry: Online (pp. 1–29). https://doi.org/10.1002/9783527628698.hgc047
[78] Sultana, B., Anwar, F., & Ashraf, M. (2009). Effect of extraction solvent/technique on the antioxidant activity of selected medicinal plant extracts. Molecules, 14(6), 2167–2180. https://www.mdpi.com/1420-3049/14/6/2167
[79] Lan, S., Wu, L., Zhang, D., Hu, C., & Liu, Y. (2011). Ethanol outperforms multiple solvents in the extraction of chlorophyll-a from biological soil crusts. Soil Biol. Biochem., 43(4), 857–861. https://doi.org/10.1016/j.soilbio.2010.12.007
[80] Sun, C., Wu, Z., Wang, Z., & Zhang, H. (2015). Effect of ethanol/water solvents on phenolic profiles and antioxidant properties of Beijing propolis extracts. Evid.-Based Complement. Altern. Med., 2015(1), 595393.
[81] Gulcin, I. (2020). Antioxidants and antioxidant methods: An updated overview. Arch. Toxicol., 94(3), 651–715.
[82] Mikucka, W., Zielinska, M., Bulkowska, K., & Witonska, I. (2022). Subcritical water extraction of bioactive phenolic compounds from distillery stillage. J. Environ. Manag., 318, 115548.
[83] Shen, L., Pang, S., Zhong, M., Sun, Y., Qayum, A., & Liu, Y. (2023). A comprehensive review of ultrasonic assisted extraction (UAE) for bioactive components: Principles, advantages, equipment, and combined technologies. Ultrason. Sonochem., 106646. https://doi.org/10.1016/j.ultsonch.2023.106646
[84] Huang, H.-W., Hsu, C.-P., Yang, B. B., & Wang, C.-Y. (2013). Advances in the extraction of natural ingredients by high pressure extraction technology. Trends Food Sci. Technol., 33(1), 54–62.
[85] Han, X., Shen, T., & Lou, H. (2007). Dietary polyphenols and their biological significance. Int. J. Mol. Sci., 8(9), 950–988.
[86] Williamson, G. (2017). The role of polyphenols in modern nutrition. Nutr. Bull., 42(3), 226–235.
[87] Somerville, V., Bringans, C., & Braakhuis, A. (2017). Polyphenols and performance: A systematic review and meta-analysis. Sports Med., 47, 1589–1599. https://doi.org/10.1007/s40279-017-0675-5
[88] Piasecka, I., Wiktor, A., & Gorska, A. (2022). Alternative methods of bioactive compounds and oils extraction from berry fruit by-products—A review. Appl. Sci., 12(3), 1734. https://doi.org/10.3390/app12031734
[89] Liu, F., Li, D., Wang, X., Cui, Y., & Li, X. (2021). Polyphenols intervention is an effective strategy to ameliorate inflammatory bowel disease: A systematic review and meta-analysis. Int. J. Food Sci. Nutr., 72(1), 14–25.
[90] Ammar, A., Trabelsi, K., Boukhris, O., Bouaziz, B., Mueller, P., & Glenn, J. M. (2020). Effects of polyphenol-rich interventions on cognition and brain health in healthy young and middle-aged adults: Systematic review and meta-analysis. J. Clin. Med., 9(5), 1598. https://doi.org/10.3390/jcm9051598
[91] Shah, K., & Shah, P. (2018). Effect of anthocyanin supplementations on lipid profile and inflammatory markers: A systematic review and meta‐analysis of randomized controlled trials. Cholesterol, 2018, 8450793.
[92] Albarri, R., & Sahin, S. (2023). Kinetics, thermodynamics, and mass transfer mechanism of the ultrasound-assisted extraction of bioactive molecules from Moringa oleifera leaves. Biomass Convers. Biorefin., 13(9), 7919–7926.
[93] Thiruvenkadam, S., Izhar, S., Yoshida, H., Danquah, M. K., & Harun, R. (2015). Process application of subcritical water extraction (SWE) for algal bio-products and biofuels production. Appl. Energy, 154, 815–828.
[94] Esfanjani, A. F., & Jafari, S. M. (2016). Biopolymer nanoparticles and natural nanocarriers for nano-encapsulation of phenolic compounds. Colloids Surf. B Biointerfaces, 146, 532–543. https://doi.org/10.1016/j.colsurfb.2016.06.053
[95] Wang, Y., Li, J., & Li, B. (2017). Chitin microspheres: A fascinating material with high loading capacity of anthocyanins for colon-specific delivery. Food Hydrocoll., 63, 293–300. https://doi.org/10.1016/j.foodhyd.2016.09.003
[96] He, J., & Giusti, M. M. (2010). Anthocyanins: Natural colorants with health-promoting properties. Annu. Rev. Food Sci. Technol., 1(1), 163–187. https://doi.org/10.1146/annurev.food.080708.100754
[97] Paes, J., Dotta, R., Barbero, G. F., & Martinez, J. (2014). Extraction of phenolic compounds and anthocyanins from blueberry (Vaccinium myrtillus L.) residues using supercritical CO2 and pressurized liquids. J. Supercrit. Fluids, 95, 8–16.
دوره 13، شماره 3
اردیبهشت 1405
صفحه 245-262
  • تاریخ دریافت: 28 مهر 1404
  • تاریخ بازنگری: 26 دی 1404
  • تاریخ پذیرش: 11 بهمن 1404
  • تاریخ اولین انتشار: 11 بهمن 1404
  • تاریخ انتشار: 01 اردیبهشت 1405